diff --git a/Zend/zend_portability.h b/Zend/zend_portability.h
index d59fc6d07c1..6ca9b7266b6 100644
--- a/Zend/zend_portability.h
+++ b/Zend/zend_portability.h
@@ -132,7 +132,7 @@
 
 #if defined(HAVE_LIBDL) && !defined(ZEND_WIN32)
 
-# if __has_feature(address_sanitizer)
+# if __has_feature(address_sanitizer) && !defined(__SANITIZE_ADDRESS__)
 #  define __SANITIZE_ADDRESS__
 # endif