diff --git a/main/main.c b/main/main.c
index 876c47549aa..8f2b8088cda 100644
--- a/main/main.c
+++ b/main/main.c
@@ -2096,7 +2096,10 @@ int php_module_startup(sapi_module_struct *sf, zend_module_entry *additional_mod
 		return FAILURE;
 	}
 #endif
+
+#ifdef ZTS
 	zend_post_startup(TSRMLS_C);
+#endif
 
 	module_initialized = 1;
 	sapi_deactivate(TSRMLS_C);